Kafkas Üniversitesi Veteriner Fakültesi Dergisi 2021 , Vol 27 , Issue 5
Haematological Profile After Use of Titanium Double Shanked Ligation Clips in Laparoscopic Appendectomy: An Experimental Study on Rat Model
Amela BAJRIĆ1, Muhamed KATICA2, Alisa SMAJOVIĆ3, Aida KATICA2, Mujo SIVIĆ1, Dunja RUKAVINA4, Amir ZAHIROVIĆ5, Ajla BAJRIĆ6, Mirza ČELEBIČIĆ7, Nasreldin HASSAN AHMED8, Samir DELIBEGOVIĆ9
1Health Institution Cantonal Hospital “Dr Irfan Ljubljankić”, Bihać, Bosnia and Herzegovina
2Department of Pathological Physiology, Veterinary Faculty, University of Sarajevo, Sarajevo, Bosnia and Herzegovina
3Department of Pharmaceutical Informatics and Pharmacoeconomics, Faculty of Pharmacy, University of Sarajevo, Sarajevo, Bosnia and Herzegovina
4Department of Biology, Veterinary Faculty, University of Sarajevo, Sarajevo, Bosnia and Herzegovina
5Department of Internal Disease, Veterinary Faculty, University of Sarajevo, Sarajevo, Bosnia and Herzegovina
6Faculty of Medicine, University of Banja Luka, Banja Luka, Bosnia and Herzegovina
7Faculty of Science, University of Sarajevo, Sarajevo, Bosnia and Herzegovina
8Emergency Medicine Clinic, University Clinical Center Sarajevo, Sarajevo, Bosnia and Herzegovina
9Surgery Clinic, University Clinical Center Tuzla, Tuzla, Bosnia and Herzegovina DOI : 10.9775/kvfd.2021.25965 The aim of the study was to determine possible adverse eff ects on haematological parameters of the rats, using diff erent surgical techniques, i.e. titanium double shanked ligation (DS) clips and endoloop polyglactin 910 suture material in laparoscopic appendectomy. The use of DS clips and other similar methods is not widely represented in veterinary surgery, as is the case in humans. Fifty rats were randomized into three groups: group 1 in which the appendiceal base was closed with a endoloop polyglactin 910 ligatures, 20 rats, group 2 in which the appendectomy was closed with DS titanium clips, 20 rats. Group 3 was the control, in which the animals were not subjected to the surgical procedure, 10 rats. Blood was drawn from the caudal vein of ten animals from each experimental group, 7 and 28 days post-surgery. Thrombocytopenia was found in the DS clips group, and hypochromia with hypochromic erythrocytes, as well as neutrophilia and lymphopenia in both experimental groups. From a haematological standpoint, DS clips are more applicable for potential patients than endoloop polyglactin 910 ligatures. Keywords : Comparison with suture material, Hypochromic anaemia, Lymphopenia, Neutrophilia, Rat