¹National Reference Laboratory of Veterinary Drug Residue and MOA Key Laboratory for the Detection of Veterinary Drugs Residues in Foods, Huazhong Agricultural University, Wuhan, Hubei 430070, CHINA
²Department of Animal Health, the University of Agricultural Peshawar, PAKISTAN
³Department of Livestock Management, the University of Agricultural Peshawar, PAKISTAN DOI : 10.9775/kvfd.2018.19910 The structural and sequences similarities of type-IV pili proteins were analysed in Pseudomonas aeruginosa, Vibrio cholerae, Neisseria meningitidis and Neisseria gonorrhoeae. Pathogenic Neisseria species possess pili-genes that code structural and assembly proteins of type-IV pili. A collection of assembly proteins reveal homology amongst P. aeruginosa and Neisseria. While in V. cholerae, these proteins ensure functional counterparts. The pilus retraction and assembly ATPases, PilB/PilF and PilT, PilU are homologous in Neisseria and P. aeruginosa, whereas V. cholerae holds only one ATPase called TcpT. In this work only type-IV pilus machinery of P. aeruginosa shows high likeness with pathogenic Neisseria. Keywords : Type IV pilus genes, Sequence similarity, Pilus machinery, Schematic overview