Kafkas Üniversitesi Veteriner Fakültesi Dergisi 2022 , Vol 28 , Issue 5
A Meta-Analysis of the Associations Between Prolactin (PRL) Gene Polymorphism and Milk Production Traits in Cattle
Zekrullah MOTMAIN1, Memiş ÖZDEMİR1, Kübra EKİNCİ1, Esranur SAYGILI1, Ebru BİLGİN1
1Department of Animal Science, Faculty of Agriculture, Ataturk University, TR-25240 Erzurum - TÜRKİYE DOI : 10.9775/kvfd.2022.27857 Th e meta-analysis method is used to combine results from many independent studies conducted in a diff erent region or area on a specific subject qualitatively and quantitatively and achieve a consensus. Th e current meta-analysis was conducted to investigate the association between prolactin gene polymorphism and milk production traits in dairy cattle. Th e data were collected between 2002 and 2021, and a total of 26 published studies were included in this study. Th e standardized mean diff erence (SMD) between genotypes was obtained for statistical evaluation, and to this end, the genetic models (dominant; AA + AB and BB, recessive; AB + BB with AA, co-dominant; AA, BB and AB genotypes) were compared with each other. In the analysis results, cattle with the AB versus BB genotype (SMD=0.289, 95% CI 0.005, 0.573) were found to have a statistically significant higher protein yield in comparison with the AA versus AB and AA versus BB genotypes. Th e relationships between prolactin gene polymorphism and milk yield, fat yield, fat content, and protein content traits were not found to be statistically significant. Keywords : PRL gene, Polymorphism, Co-dominant, Meta-analysis, Standardized mean diff erence