Kafkas Üniversitesi Veteriner Fakültesi Dergisi 2022 , Vol 28 , Issue 5
Potential of Glycyrrhiza glabra (Licorice) Extract an Alternative Biochemical and Therapeutic Agent Against Coccidiosis in Broiler Chickens
Kashif HUSSAIN1, Abdullah F. ALSAYEQH2, Asghar ABBAS1, Rao Zahid ABBAS3, Atif REHMAN1, Waqar ZAIB1, Tauseef Ur REHMAN4, Muhammad Shahid MAHMOOD5
1Department of Pathobiology, Faculty of Veterinary and Animal Sciences, Muhammad Nawaz Sharif University of Agriculture, Multan, 66000, PAKISTAN
2Veterinary Medicine, College of Agriculture and Veterinary Medicine, Qassim University, Buraidah, 6622 Postal code: 51452, SAUDI ARABIA
3Department of Parasitology, Faculty of Veterinary Sciences, University of Agriculture Faisalabad, 38000, PAKISTAN
4Department of Parasitology, Th e Islamia University of Bahawalpur, 63100, PAKISTAN
5Institute of Microbiology, University of Agriculture Faisalabad, 38000, PAKISTAN
DOI : 10.9775/kvfd.2022.27620 To control coccidiosis, anticoccidials are generally used as feed additives. However, the frequent usage has given rise to the occurrence of resistant strains to available anticoccidial drugs. Botanicals may work as substitutes to anticoccidial drugs. Th e current research was designed to evaluate the efficacy of aqueous methanol extracts of Glycyrrhiza glabra (licorice) (roots) as anticoccidial in diff erent concentrations i.e. (100, 200 and 300 mg/kg of body weight). For in vivo trial, 105-day-old broiler birds were grouped into seven equal groups (A, B, C, D, E, F and G). At the age of one week, groups A, B and C were orally treated with three doses of the G. glabra extracts (100, 200 and 300 mg/kg of body weight, respectively). Group D was medicated with Vitamin E and Group E worked as the infected medicated control group. Group F served as the infected non-medicated control group (PBS treated, negative control) and Group G was designated as the normal control group (non-infected and nonmedicated group). At the age of the 14th day, all groups were infected orally with 60.000 sporulated oocysts of diff erent Eimeria species. Th ough, comparable with reference drug G. glabra showed comparable anticoccidial efficacy against following parameters. i.e., feed conversion ratio, lesion score, fecal score and oocyst score, serum profile and hematological values showed no adversative eff ects (P<0.05) than infected non-medicated (negative control) group of aqueous methanol extract of G. glabra on the trial broiler birds. So, in this study the biochemical and therapeutic property of G. glabra extract found dose dependent manner against coccidiosis in broiler chickens. Keywords : Phytomedicine, Poultry, Alternatives, Disease