¹Department of Internal Medicine, Faculty of Veterinary Medicine, University of Aksaray, TR-68100 Aksaray - TURKEY
²Aksaray Technical Sciences Vocational School, University of Aksaray, TR-68100 Aksaray - TURKEY
³Department of Internal Medicine, Faculty of Veterinary Medicine, University of Aydin Adnan Menderes, TR-09100 Aydın - TURKEY
⁴Department of Genetics, Faculty of Veterinary Medicine, University of Van Yuzuncu Yil, TR-65080 Van - TURKEY DOI : 10.9775/kvfd.2019.22083 Sarcoptic mange, a notable parasitic disease, causes dermatological alterations among ruminants. Thiol-disulphite hemostasis is a novel oxidative stress parameter. The aim of this study was to evaluate dynamic thiol/disulfide homeostasis in sheep with sarcoptic mange. Total of thirty-six sheep (n=15 female, n=21 male) with sarcoptic mange (Group I), and twelve healthy sheep (Group II) were used in the study. A novel method was used to determine the thiol disulphide parameters. Native thiol, total thiol and Disulphide values were statistically lower in Group I. Disulphide/native thiol, Disulphide/total thiol, and Native thiol/total thiol proportions had no statistical differences in groups. Sarcoptic mange was probably affected by the thiol Disulphide hemostasis in infected sheep. Thus, the data obtained in this study might form base for further studies to include antioxidant molecules in the treatment protocols. Keywords : Oxidative stress, Sarcoptic mange, Sheep and Thiol disulphide