¹University of Kafkas, Faculty of Veterinary Medicine, Department of Food Safety and Public Health, TR-36100 Kars - TURKEY DOI : 10.9775/kvfd.2017.19134 The use of antibiotics in food animals creates an important source of antimicrobial resistant bacteria that can spread to humans through the food chain. Strains of Salmonella spp. with resistance to antimicrobial drugs are now widespread in all countries. The present study analysed the prevalence and antimicrobial resistance of Salmonella spp. isolates in raw chicken wings. Out of 200 fresh raw chicken wing packages 102 (51%) samples were positive. Antibiotic resistance test was performed on 200 isolates out of 336 after being confirmed. All the isolates showed multiple resistance against the antibiotics investigated with the average 0.371 multiple antibiotic resistance (MAR) index. None of the isolates were resistant to amoxicillin/clavulanate and cefoxitin. Only 2 isolates showed intermediate resistance to imipenem. The major resistance was observed against nalidixic acid (95%), trimethoprim/sulfomethoxazole (92%), tetracycline (92%), streptomycin (90%) and trimethoprim (81%). Even though only 4 isolates were resistant against ciprofloxacin, high percentage of intermediate resistance (92%) was detected. Some of the isolates were also resistant to gentamicin (7%), cefoperazone (2%), ampicillin (24%), chloramphenicol (24%), cephazolin (7%) and cefotaxime (39%). According to our results high prevalence and the increase in antibiotic resistant Salmonella spp. is of concern and constitutes a threat to public health. Keywords : Salmonella, Chicken, Antibiotic resistance