Kafkas Üniversitesi Veteriner Fakültesi Dergisi 2018 , Vol 24 , Issue 3
Determination of Some Acute Phase Proteins, Biochemical Parameters and Oxidative Stress in Sheep with Naturally Infected Sheeppox Virus
Kadir BOZUKLUHAN, Oğuz MERHAN, Halil İbrahim GÖKÇE, Metin ÖĞÜN, Emine ATAKİŞİ, Şemistan KIZILTEPE, Gürbüz GÖKÇE
1University of Kafkas, Kars School of Higher Vocational Education, TR-36100 Kars - TURKEY
2University of Kafkas, Department of Biochemistry, Faculty of Veterinary Medicine, TR-36100 Kars - TURKEY
3University of Mehmet Akif Ersoy, Department of Internal Medicine, Faculty of Veterinary Medicine, TR-15000 Burdur - TURKEY
4University of Kafkas, Department of Internal Medicine, Faculty of Veterinary Medicine, TR-36100 Kars - TURKEY
DOI : 10.9775/kvfd.2017.19167 The aim of the present study was to determine oxidative stress and acute phase response in naturally infected sheep with poxvirus. For this purpose, 20 poxvirus infected and 10 clinically healthy sheep were used in the study. In these animals, alkaline phosphatase (ALP), aspartate aminotransferase (AST) activity, haptoglobin, ceruloplasmin, urea, creatinine, albumin, iron (Fe), malondialdehyde (MDA) and reduced glutathione (GSH) concentrations were determined. The present study determined that the concentrations of haptoglobin, ceruloplasmin, urea, creatinine, MDA and ALP, AST activity were significantly increased, and albumin, Fe and GSH concentrations were significantly decreased in the sheeppox virus infected group compared to the control group. Results of this study indicated that oxidative stress and acute phase response develop in sheep infected with poxvirus. Keywords : Acute phase proteins, Biochemical parameters, Sheeppox