¹Department of Pathology,Faculty of Veterinary Medicine, Firat University, TR-24200 Elazig - TURKEY
²Department of Medical Microbiology, Faculty of Medicine, Inonu University, TR-44280 Malatya - TURKEY
³Department of Food Hygiene and Technology, Faculty of Veterinary Medicine, TR-24200 Elazig - TURKEY
⁴Department of Virology, Faculty of Veterinary Medicine, Firat University, TR-24200 Elazig - TURKEY DOI : 10.9775/kvfd.2018.19952 Clostridial enterotoxemia caused by Clostridium perfringens type E was diagnosed postmortem in a 2-months-old calf in a family farm containing 20 cattle at different ages. Varying degrees of severity of segmental fibrino-hemorrhagic and necrotic enteritis was present at the necropsy. Clostridium perfringens was isolated from the intestinal tissue and intestinal content and the genes encoding alpha and iota toxins were detected by polymerase chain reaction (PCR). Histopathological examination showed the presence of adherent Gram-positive rods on the surface of villi and in poly morphonuclear leucocytes in the lamina propria of the intestinal mucosa.Overall, the results of the present study suggest that C. perfringens type E should be can be considered at differential diagnosis in fibrino-hemorrhagic enteritis and sudden deaths in post weaned calves. Keywords : Bovine, Clostridium perfringens type E, Enterotoxemia