Kafkas Üniversitesi Veteriner Fakültesi Dergisi 2017 , Vol 23 , Issue 6
Evaluation of Immunotherapeutic Effects of Aloe vera Polysaccharides
Kashfa KHALIQ, Masood AKHTAR, Mian Muhammad AWAIS, Muhammad Irfan ANWAR
1Department of Microbiology, Govt. College University, Faisalabad, PAKISTAN
2Department of Parasitology, University of Agriculture, Faisalabad, PAKISTAN
3Department of Pathobiology, Faculty of Veterinary Sciences, Bahauddin Zakariya University, Multan, PAKISTAN
DOI : 10.9775/kvfd.2017.17957 This study reports the immunotherapeutic effects of Aloe (A.) vera polysaccharides against coccidiosis in broiler chicken. For the purpose, polysaccharides were recovered from A. vera and analyzed by using HPLC. Three different hexose sugars including maltose, glucose and mannose were detected in hydrolyzed solution of A. vera. The extracted polysaccharides (graded doses) were evaluated for immunotherapeutic activities against coccidiosis in chicken. Results revealed that percent protection and daily weight gains were significantly higher (P<0.05) in chicken administered with A. vera polysaccharides as compared to control group. On the other hand, oocyst counts and lesion scores were lower (P<0.05) in polysaccharides administered chickens as compared to control. Moreover, anti-coccidial indices were also higher in chickens administered with polysaccharides (159.75-239.63) as compared to control (36.57). Except spleen, the organ-body weight ratios of all lymphoid organs of experimental and control groups were statistically similar (P>0.05). Based upon findings of this study, it was concluded that A. vera derived polysaccharides had immunotherapeutic activity against coccidiosis in chickens and might be further explored for its commercial feasibility for effective use in poultry industry to control avian coccidiosis. Keywords : Immunotherapeutic, Aloe vera , Polysaccharides, Coccidiosis, Chicken